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  • MSG, is a sodium salt of glutamic acid. MSG is a food additive, popularly marketed as a "flavour enhancer. It was discovered and patented in 1909 by Ajinomoto Corporation in Japan. In its pure form, it appears as a white crystalline powder; when dissolved in water (or saliva) it rapidly dissociates into free sodium and glutamate ions.
  • Glutamate itself is a widespread amino acid: it is found naturally in human bodies, and is found primarily in the bound form in protein-containing foods, such as mushrooms, seaweed, tomatoes, nuts, legumes, meats, and most dairy products. Only a fraction of the glutamate in foods is in a "free" form, and only free glutamate can enhance the flavour of foods. Part of the flavour-enhancing effect of tomatoes, fermented soy products, yeast extracts, certain sharp cheeses, and fermented or hydrolyzed protein products (such as soy sauce and soy bean paste) is due to the presence of free glutamate ions.
  • MSG is usually produced through fermentation — a process similar to that used in making vinegar and yogurt. The process begins with the fermentation of corn, sugar beets, or sugar cane. The finished product is a pure, white crystal, which dissolves easily and blends well with many foods. The fermentation method has the advantage of mass production at low cost, which was the great impetus for expanding the amino acid market. The manufacturing method of glutamate shifted from the extraction method to the fermentation method in the 1960s. Subsequently, a similar shift to the fermentation method took place for the other amino acids in rapid succession.
  • The most relevant factors influencing L-glutamate formation are the ammonium concentration, the dissolved 02 concentration and the pH. Although, in total, a large amount of ammonium is necessary for sugar conversion to L-glutamate, a high concentration is inhibitory to growth as well to the production of L-glutamate. Therefore, ammonium is added in a low concentration at the beginning of the fermentation and is then added continuously during the course of the fermentation. The oxygen concentration is controlled, since under conditions of insufficient oxygen, the production of L-glutamate is poor and lactic acid as well as succinic acid accumulates, whereas with an excess oxygen supply the amount of a-ketoglutarate as a by-product accumulates.
  • MSG helps bring out the best natural flavors in a variety of foods such as meat,poultry, seafood, and vegetables. Soups, casseroles, gravies, and sauces are examples of dishes that can benefit from the proper use of MSG.While MSG harmonizes well with salty and sour tastes, it contributes little or nothing to sweet or bitter foods.
  • Glutamate occupies a central position in human metabolism. It comprises between 10 – 40% by weight of most proteins, and can be synthesised in vivo. Glutamate supplies the amino group for the biosynthesis of all other amino acids, is a substrate for glutamine and glutathione synthesis, is an key neurotransmitter in the brain and is also an important energy source for certain tissues. Breast milk concentrations of glutamate are only modestly influenced by the ingestion of MSG and the placenta is virtually impermeable to glutamate. Although glutamate is an important neurotransmitter in the brain, the blood brain barrier effectively excludes passive influx of plasma glutamate.
  • Monosodium glutamate, which is present as glutamic acid in the acidic environment of the stomach, is metabolized in the same way that the glutamic acid from the proteins of a normal diet is metabolized. Since the 80 grams of protein in the normal diet contain about 15 grams of glutamic acid, one would not expect an additional fraction of a gram of MSG consumed as a flavor enhancer to cause a health problem.
  • Brazil is the world's top producing country of sugar cane, the main raw material of MSG. The MSG global market is approximately 1,700,000MT, with a projected annual growth rate of 4 per cent. Ajinomoto claims to have a 34 per cent share of the market. In Vietnam Ajinomoto intends to lift annual MSG production capacity from 45,000MT to 60,000MT with construction slated for completion by mid-2006.
  • The MSG manufacturers and Government of Indonesia officials determined that the color of the fortified MSG must not deviate from the color of unfortified MSG. MSG is marketed in clear multilaminate packets showing its purity. Various initial attempts to coating the 250 CWS VA were tried including agglomeration of the VA beadlets with small MSG crystals or whitening of the beadlets with Klucel (hydroxypropylcellulose) -TiO2 combination. The whitening options were chosen to mask the yellow color of the VA beadlets. Due to the successful field bioavailability study, the chemical stability of VA in fortified MSG was not considered.
 General Information
  • Monosodium Glutamate
  • Facts on Monosodium Glutamate
  • Some Background on MSG
  • Monosodium glutamate - Ingredients
  • Product Identification of Monosodium Glutamate
  • Description of Monosodium glutamate

Production and Processing

  • Production Process of MSG
  • Production of Monosodium Glutamate by Fermentation
  • Industrial Production of L-Glutamine1
  • Amino Acid Production
  • Efficiency of Glutamine Production by Coupling of a Bacterial Glutamine Synthetase Reaction with the Alcoholic
    Fermentation System of Baker’s Yeast
  • L-Glutamine Formation by Flavobacterium rigense
  • Production Methods of Amino acids
  • Production of Glutamine
  • Manufacturing Process of MSG
  • Commercial Production of MSG
  • Muscle glutamine production in diabetic ketoacidotic rats


  • Function of Glutamate
  • Food coloring and monosodium glutamate: effects on the cephalic phase of gastric acid secretion
  • Function of Group III metabotropic glutamate receptors in rat pancreatic islets
  • Gustatory Responsiveness to Monosodium Glutamate in Four Species of Nonhuman Primates
  • Many-faceted mystique of monosodium glutamate
  • Responses to Monosodium L-Glutamate in Taste Receptor Cells of Rat Fungiform Papillae
  • Vitamin A-fortified monosodium glutamate and health, growth, and survival of children: a controlled field trial
  • An enzymatic process to a-ketoglutarate from L-glutamate


  • Physical and chemical properties of MSG
  • Properties of Monosodium Glutamate
  • Kinetic Properties of Monosodium Glutamate
  • Intramolecular Carbon Isotopic Composition of Monosodium Glutamate
  • Novel Synthesis of Gold Nanoparticles in Aqueous Media
  • Therapeutic Properties of Monosodium Glutamate

Company Profiles

  • Hebei Meihua Monosodium Glutamate Group Co., Ltd.
  • Ajinomoto
  • Dachuan
  • Daesang Corporation
  • NORPAC Foods
  • Vinythai


  • Australian Glutamate Information Service
  • Expert in Monosodium Glutamate
  • Glutamate Information Service
  • L. Hepner & Associates
  • CPL Business Consultants
  • Home Allergy Design Consultants
  • International Glutamate Information Service

Project and Plant

  • Treatment of wastewater from a monosodium glutamate manufacturing plant
  • Carcinogenic Potency Project
  • Peripheral and central contributions to monosodium glutamate synergism
  • Jiangsu Environmental Technical Support (JETS) Project
  • Thailand Plant
  • Vedan MSG Producing Plant


  • Uses of MSG
  • Manufacturing of Imitation crab meat using MSG
  • Production of Red Pigments by Monascus ruber
  • Synergic treatment for monosodium glutamate wastewater by Saccharomyces cerevisiae
  • Manufacturing of Condensed soup using MSG
  • Use and Utility of Glutamates as Flavoring Agents in Food
  • Uses of Monosodium glutamate

Material Safety Data Sheet

  • Monosodium Glutamate FCC Crystals
  • L-Glutamic acid
  • Sodium Salt
  • Monosodium Salt Monohydrate
  • Monosodium Glutamate
  • Safety data for monosodium glutamate
  • Centrifugal Separating Technology
  • Evaporation Technology
  • Starch and Industrial Biotechnology
  • Monosodium Glutamate Technology
  • New Technology of Monosodium Glutamate
  • Green Technology of Monosodium Glutamate


  • Process for the preparation of monosodium glutamate
  • Formulation of adenovirus for gene therapy
  • Composition comprising monosodium glutamate for use in relieving fatigue
  • Flowable cottonseed and method for its preparation
  • Granular Chemical Seasoning og High Specific Volume and Production Thereof
  • Process for producing glutamic acid

Market and Report

  • Ajinomoto ramps up MSG production on market growth
  • Fermentation and Enzyme Industry in China
  • Glutamate industry involvement is rarely obvious
  • Industry defends MSG
  • Conditional Sale Of Monosodium Glutamate Unit To Ajinomoto
  • Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture
  • FDA and Monosodium Glutamate
  • Analysis for the presence of Monosodium Glutamate (MSG) in the VIBETM Nutraceutical
  • Glutamate and Monosodium Glutamate: Examining the Myths
  • Imports and Exports of Monosodium Glutamate
  • MSG Slowly Poisoning America
  • Draft  Assessment Report
  • EPA Report


  • Aji No Moto Monosodium Glutamate
  • Assam Laksa Flavour
  • Fresh Kielbasa
  • List of Monosodium Glutamate Products
  • Ajinomoto
  • Ramen noodles
  • Pure Monosodium Glutamate Powder

 Manufacturers, Suppliers and Buyers

  • Monosodium Glutamate Exporters
  • Trade Leads of Monosodium Glutamate
  • Suppliers of Monosodium Glutamate
  • Monosodium Glutamate Manufacturers
  • Manufacturers of Monosodium Glutamate
  • Trade offers of Monosodium Glutamate
  • Selling Leads Monosodium Glutamate
  • Monosodium Glutamate Suppliers
  • Traders of Monosodium Glutamate
  • Monosodium Glutamate Buyers List

Equipments Suppliers

  • Centrifuge Suppliers
  • Chemical Dryers Suppliers
  • Crystallizer Suppliers
  • Dissolver Suppliers
  • Evaporator Suppliers
  • Fermenter Suppliers
  • Filter Suppliers
  • Swenson Crystallization Equipment

Health Hazards

  • Health Hazards of MSG
  • MSG Hazards
  • Slow Poisoning - MSG (Monosodium Glutamate)
  • Monosodium Glutamate (MSG) Toxicity
  • Glutamate Safety in the Food Supply
  • Toxicity of free Glutamic Acid
  • MSG - Slow Poisoning: The Cause Of Obesity and Other Health Problems
  • Health Hazards of Monosodium Glutamate

 Safety and Guides

  • Safety Issues of Monosodium Glutamate
  • Is MSG safe for children
  • Ajinomoto: To Use Or Not To Use
  • Food labeling rules regarding MSG
  • Information about obesity and other effects of processed free glutamic acid (MSG)
  • Monosodium Glutamate: Food for Thought but not for Eating
  • FAQ's about Monosodium Glutamate

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