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  • Carboxylic acid derivatives are compounds with functional groups that can be converted to carboxylic acids by a simple acidic or basic hydrolysis. They include esters, amides, nitriles, acid halides, and acid anhydrides.
  • Reaction of -OH and -COOH on same molecule produces a cyclic ester, lactone.
  • Esters are named as alkyl carboxylates.Alkyl from the alcohol, carboxylate from the carboxylic acid precursor.
  • Acyl intermediates include acyl anions, acyl radicals and acyl cations (synonym: acylium ions) which are formally derived from oxoacids RkE(=O)l(OH)m (l not equal to 0) by removal of a hydroxyl cation HO+, a hydroxyl radical HO. or a hydroxyl anion HO-, respectively, and replacement analogues of such intermediates.
  • The reaction of a carboxylic acid and an alcohol yields an ester and water is eliminated.
  • A recent synthesis (4) made S-alkyl thiohydroxamic acids readily available, though in every case only one isomer, inferred to be the anti form, was isolated.
  • Active N-acyl, derivatives of a-amino acids are rapidly racemized by acetic anhydride at room temperature.
  • Acyl derivatives of ara-C4 with long linear saturated fattyacids at the A/4 position of ara-C exhibited a higher antitumor activity than did ara-C in the mouse leukemia L1210 system.
  • A large number and wide variety of acyl derivatives of the tylosin-related macrolides 23-demycinosyltylosin (DMT), 23-demycinosyloxytylosin DMOT) and 5-O-mycaminosyltylonolide (OMT) were synthesized and evaluated.
  • Analysis of the kinetics of hydrolytic and other transacylation reactions catalyzed by a-chymotrypsin yields two kinds of kinetic parameters.
  • Acylation is one of the fundamental reactions in organic chemistry and can be carried out by wide variety of reagents. Acyl groups play an important role in the chemistry of biomolecules.
  • Ester enolates which is a derivative of corboxylic acid derived from alkyl esters of alkanoic acids react with carbony1 compounds in an aldol type reaction forming alkyl @-hydroxyalkanoates.
  • N-alkylation, N-acylation, and Nhydroxyacylation, type of organic compound used in each of N-substitution reactions to ultimately enhance the bioactivity of chitosan.
  • The ideal acylating reagent would be a carboxylic acid, but the acids themselves are relatively unreactive with nucleophiles. A simple solution to this inactivity, as noted earlier, was to convert the carboxylic acid to a more reactive derivative such as an acyl chloride or anhydride.
  • Chiral phase HPLC has mainly been applied to pharmaceutical molecules but Chapter 7 shows how it can be used to separate enantiomers of monacyl and diacylglycerols.
  • The development of acyl derivatives was determined by borohydride reduction technique.
  • Polybutadiene with a narrow molecular weight is synthesized by anionic polymerization of butadiene monomer in cyclohexane at 20 ' C using
    n-butyllithium as Initiator .The amount of urazole and acyl incorporation are determined by 1H NMR technique.
General Information
  • Carboxylic Acids and Derivatives
  • Introduction - Carboxylic Acid Derivatives
  • Carboxylic Acid Derivatives and Nitriles
  • Nomenclature of Carboxylic Acid Derivatives
  • Carboxylic Acid Derivatives. Nucleophilic Acyl Substitution 

Company Profile

  • China Company
  • Company from China
  • Company from Germany
  • Company from Israel
  • US Company from Texas
  • Company from California
  • Company from USA


  • Consultant from Minnesota
  • Consultant from New York
  • Consultant from Texas
  • Consultant from UK
  • Consultant from USA
  • Consultant from California


  • Acyl derivatives I
  • Acyl derivatives II
  • Acyl derivatives of Hydroxylamine. XIII. Configuration and conformation of hydroxamic acid derivatives containing sulfur
  • Carboxylic Acid Derivatives
  • Enzyme Catalyzation of the Deacylation of N4-Acyl Derivatives of 1 Arabinofuranosylcytosine in the Mouse Liver Microsome
  • Synthesis and Antimicrobial Evaluation of acyl derivatives of 16-membered macrolide antibiotics related to tylosin
  • S-Acyl Derivatives of Benzothiazole-2-thiol: A Convenient Method for the Synthesis of Amides and Carbamates
  • A Quantitative Analysis of the binding of N-Acyl Derivative of a-aminoacids by a chymotrypsin
  • Carboxylic Acid Derivatives A Substitution Reaction Which Starts With Addition
  • Enzymatic Reduction of Alkyl and Acyl Derivatives of Dihydroxyacetone Phosphate by Reduced Pyridine Nucleotides
  • Study on the reactions of azo compounds with acyl halides mediated by Sm/TiCl4


  • Adducts from the Reaction of O, O'-Diacetyl or O-Acetyl Derivatives of the Carcinogen 4-Hydroxyaminoquinoline 1-Oxide with Furine
  • 1-acyl-3-hydroxy-1H-pyrazoles and related derivatives as useful acylating agents
  • Application of enolates of activated carboxylic acid derivatives in organic synthesis-novel syntheses of p-lactones
  • Esters as Food Flavourings
  • Fatty Acyl Derivatives of Glucosamine 1-Phosphate in Escherichia coli and Their Relation to Lipid A
  • Liquid - Chromatographic DetermInation of Tocainide in Plasma,with N-Acyl Derivatives of Tocalnideas Internal Standards.
  • On Carboxyl Activation for Peptide Synthesis
  • Vitamin B12-mediated electrochemical reactions in the synthesis of natural products
  • The Synthesis of water soluble N Acyl chitosan derivatives for characterization as antibacterial agents


  • Specialized Acylation Reagents and Techniques
  • Amino-Acids, Acyl-Amino-acids, Dipeptides, Acyl-Dipeptides and Derivatives of these Compounds by Absorption Spectra
  • HPLC of Acyl Lipids
  • The development of methods f o r measurement of Labile Acyl Derivatives
  • Acylation of Polybutadiene Containing 4-Phenyl Urazole
  • Prediction of Acidity Constants of Thiazolidine-4-carboxylic Acid Derivatives Using Ab Initio and Genetic Algorithm-Partial Least Squares
  • New Synthetic Route to Acylated Ferrocene Derivatives for Controlling the CisPlat Drug

  • Classification of Organic Compounds
  • Cyclic AMP Directly Activates NasP, an N-Acyl Amino Acid Antibiotic Biosynthetic Enzyme Cloned from an Uncultured -Proteobacterium
  • Collaborative Industrial/Academic Research on Alternate Phosgene Chemistry for Environmentally Benign Chemical Synthesis and Processing
  • Outline & Study Guide for Unit V. Carboxylic Acids & Derivatives
  • Introducing chirality in Multicomponent Reaction: a combined theoretical and experimental study
  • Cellular events and molecular mechanisms underlying sex pheromone production in the silkmoth, Bombyx mori


  • Acyl Derivatives 1
  • Acyl Derivatives 2
  • Esters on Unsaturated carboxylic acids
  • N-Acyl Derivatives of aminoalcohols with polycarboxylic acids able to modulate mast cells in inflammatory processes having neuroimmunogenic origin
  • Substituted acyl derivatives of aminoacids
  • Use of Acyl Derivatives of aminoalcohols in the manufacture of a medicament for practicing neuroprotective action in neuropathological atates connected with excitotoxicity

Properties & Function

  • Antiviral Activities of Acyl Derivatives of 2,2'-Anhydro-1-f3- D-Arabinofuranosylcytosine and 1-/3-DArabinofuranosylcytosine in Cell Culture
  • Synthesis and biological activities of turkesterone 11α-acyl derivatives
  • 3-O-Acyl Derivatives of Bridged-15-Membered Azalides: Synthesis, Structural Determination and Antibacterial Activity
  • N-Acylated and D Enantiomer Derivatives of a Nonamer Core Peptide of Lactoferricin B Showing Improved Antimicrobial Activity
  • Molecular Properties of Acyl Carrier Protein Derivatives

Report & Market

  • Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation
  • Perfluorinated Carboxylic Acids (PFCAs) and Precursors: A Proposed Action Plan for Assessment and Management
  • Free Radical Acylation Approach of Carbohydrate Derivatives
  • Identification of zomepirac-S-acyl-glucuronide in vitro in incubations with rat Hepatocytes and in vivo in rat bile
  • (4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase
  • Synthesis and Tautomeric Studies of Enamines from 1-(n-Hexyl)-3-methyl-2-pyrazolin-5-one
  • Oxea to Produce Carboxylic Acids in China; Joint Venture with Shenyang Zhangming Chemical Planned

Suppliers & buyers

  • Suppliers of Esters
  • Suppliers of Amides
  • Suppliers of Acid Anhydrides
  • Suppliers of  Nitriles
  • Suppliers of Acid Halides
  • Buyers of Esters
  • Buyers of Amides

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